Consuming a carbohydrate-rich food as the final food in a meal, as compared to the first food in a meal, has been shown to reduce blood glucose levels after eating in both diabetes patients and in healthy controls. However, gaps remain in the literature in this area of research, and currently little is known about how substrate (fuel) use is impacted by altering food order. In addition, most studies to date have used a mix of meat and plant foods, while little research has focused exclusively on vegetarian foods. This randomized experiment will examine how altering the order of foods eaten in a vegetarian meal impacts blood glucose and fuel utilization at rest.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
60
Rice eaten first (150 grams), followed by edamame (150 grams) and butter (10 grams)
Edamame (150 grams) and butter (10 grams) eaten first, followed by rice (150 grams)
Old Dominion University Human Performance Laboratory
Norfolk, Virginia, United States
RECRUITINGRespiratory exchange ratio
Ratio of carbon dioxide production and oxygen consumption for determination of fuel use
Time frame: 90 minutes (baseline/premeal and at 30, 60, and 90 minutes postmeal)
Fat use
Fat utilization will be estimated from respiratory gas exchange
Time frame: 90 minutes (baseline/premeal and at 30, 60, and 90 minutes postmeal)
Carbohydrate use
Carbohydrate utilization will be estimated from respiratory gas exchange
Time frame: 90 minutes (baseline/premeal and at 30, 60, and 90 minutes postmeal)
Blood glucose
Blood glucose will be measured with fingerstick samples and a portable glucometer
Time frame: 90 minutes (baseline/premeal and 30, 60, and 90 minutes postmeal)
Hunger-satiety perceptions
Hunger, appetite, satiety, and fullness on a 0-10 Likert scale
Time frame: 90 minutes (baseline/premeal and 30, 60, and 90 minutes postmeal)
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