The Study Aims to Measure the Metabolome in Melanoma Patients Using NMR Spectroscopy and Gas Chromatography and to Analyse Differences Depending on the Course of the Disease.

Technische Universität Dresden3,000 enrolled

Overview

Prospective, single-centre study with the central question of how the metabolome from blood samples, different body fluids and tissues between patients patients with malignant melanoma in different tumour tumour stages and healthy patients and whether this is suitable for early detection of initial diagnosis, recurrence or stage shift at an early stage. The biosamples are collected in the BioBank Dresden and used for the NMR and LC-MS analyses described here. It is planned to use the biosamples for further analyses.

Study Type

OBSERVATIONAL

Enrollment

3,000

Conditions

Melanoma of Skin

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Current or past history of melanoma * Ongoing therapy or tumour aftercare at the Skin Cancer Centre at Dresden University Hospital Exclusion Criteria: * Refusal to participate in the study * Lack of capacity to consent

Locations (1)

University Hospital Carl Gustav Carus

Dresden, Saxony, Germany

Outcomes

Primary Outcomes

Differences in metabolite concentrations

Metabolite concentrations are measured by NMR spectroscopy and gas chromatography and compared between different subgroups.

Time frame: through study completion, an average of 3 years