Magnesium is essential in human physiology. Simultaneous pancreas-kidney (SPK) transplant recipients frequently experience hypomagnesemia. The effects of hypomagnesaemia are harmful. This observational study assessed intraoperative magnesium supplementation's utility in patients undergoing SPK transplantation. Perioperative hemodynamics were monitored. Postoperative serum magnesium was monitored at 12 hours and 48 hours.
A vital component of human physiology is magnesium. It is common for recipients of simultaneous pancreas-kidney (SPK) transplants to have hypomagnesemia. The consequences of hypomagnesaemia are detrimental. This prospective observational study evaluated the effectiveness and safety of intraoperative magnesium supplementation in adult SPK transplant recipients. Arrhythmia and perioperative hemodynamics were observed. Serum magnesium levels were checked 12 and 48 hours after surgery.
Study Type
OBSERVATIONAL
Enrollment
40
Patients undergoing simultaneous pancreas-kidney (SPK) transplantation who gave their consent were given an intravenous magnesium supplement at a dose of 45-50 mg/kg over the course of an hour during the procedure.
Central Manchester University Hospital
Manchester, Manchester, United Kingdom
Serum magnesium levels.
Serum magnesium levels after surgery at 12 and 48 hours.
Time frame: 48 hours
Perioperative cardiovascular incidents.
Incidence rate of intraoperative and postoperative dysrhythmia events for each patient.
Time frame: 48 hours
Postoperative neurological incidents.
Incidence rate of postoperative confusion, muscle spasms, or weakness in each patient.
Time frame: 48 hours
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