Phase III Trial of Susu Zhike Granules in Children With Cold-cough Syndrome for Acute Cough Treatment

Inclusion Criteria: 1. It met the diagnostic criteria for common cold, and the severity VAS score of day or night cough was ≥40 mm ，the cough symptom score was ≥2 points; 2. Conforming to the standard of wind-cold cough differentiation; 3. Age 6-13 years old (6 years old ≤ age \< 14 years old); 4. Duration of cough ≤48 hours; 5. Maximum axillary temperature ≤38℃ within 24 hours before diagnosis; 6. The informed consent process should be in accordance with the regulations, and the legal guardian or the subject child (≥8 years old) should sign the informed consent. Exclusion Criteria: 1. accompanied by pharyngeal swelling pain, heat image is obvious; 2. White blood cell count, neutrophils absolute value, C-reactive protein, all exceeded the upper limit of 1.2 times the reference value, and the researchers considered the bacterial infection; 3. there have been complications (bacterial otitis media, sinusitis, suppurative tonsillitis, bronchitis, bronchopneumonia); 4. Patients with acute bronchitis and pneumonia cured less than 8 weeks; 5. People with a history of seasonal or perennial allergic rhinitis, chronic sinusitis, chronic otitis media, bronchial asthma, chronic cough or recurrent respiratory infections; 6. Other acute episodes of nasal diseases (vasomotor rhinitis, drug rhinitis, etc.), nasal foreign body, or foreign body inhalation, any anatomical respiratory abnormalities; 7. Patients with serious systemic diseases or mental disorders such as cardiovascular, brain, liver, kidney and hematopoietic system; 8. Those who had used Chinese and Western drugs and therapies that had influence on the effectiveness evaluation of the experimental drugs within 24 h before enrollment; 9. Allergic to known components of the investigational drug; 10. Those who participated in other clinical trials and took investigational drugs within the past one month; 11. Those who were not considered suitable for inclusion by the researchers.