This is a single-blinded study. Participants will be randomly assigned to self-initiated perturbation-based balance training (SePBT) group or control (conventional balance training) group. Kinematic and Kinetic changes following SePBT group compared to control will be investigated.
Participants will be randomly assigned to two groups receiving SePBT or control group. All participants will give their written informed consent before baseline assessment. The study will be reported and conducted in line with the CONSORT statement. Participants will be recruited via convenient sampling in the local community. After baseline assessment, both groups will go through two 30-minute training session over two weeks. Between-group differences in behavior will be examined before and after training to identify training-induced changes in postural stability. Retention of the changes in the postural stability will be assessed four months after the training period. Incidents of falls will be followed up for 12 months after training.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
SINGLE
Enrollment
48
This group will receive two 30-minute training sessions over two weeks, with one session per week. Participants will be required to recover their balance upon self-initiated perturbation.
This group will receive two 30-minute training sessions over two weeks, with one session per week. Participants will be instructed to perform balance and strength training. The same training duration and format will be used as the Self-initiated perturbation-based balance training group.
The Hong Kong Polytechnic University
Hong Kong, Hong Kong, Hong Kong
RECRUITINGPostural stability
Postural stability at the recovery steps after the perturbation will be calculated as the distance between the absolute center of mass (CoM) position in an anteroposterior direction relative to the closest edge of the Base of Support (BoS) normalized by foot length. The absolute CoM position and BoS position will be traced by the motion capture system synchronized with the force plates embedded underneath the slip-treadmill belts.
Time frame: Pre-intervention, 1 week after intervention and 4 months after intervention.
Generic balance ability
Generic balance ability will be assessed by the Mini-BESTest. It contains 8 test items and each item will score between 0 and 3 and the total scores will range from 0 to 24, with higher scores denoting better balance ability.
Time frame: Pre-intervention, 1 week after intervention and 4 months after intervention.
Mobility
Mobility will be assessed by Timed Up and Go test (in the unit of seconds).
Time frame: Pre-intervention, 1 week after intervention and 4 months after intervention
Number of real-life falls
The number of real-life falls in months after randomization will be recorded. Fall circumstances and related injuries will be required via phone contact. A fall is defined as an event resulting in a person unintentionally coming to rest on the ground or other lower level, not as the result of a major intrinsic event (e.g., syncope, stroke, or overwhelming hazard such as an earthquake).
Time frame: 1 month, 2 months, 3 months, 4 months, 5 months, 6 months, 7 months, 8 months, 9 months, 10 months, 11 months, and 12 months after the intervention.
Responsive postural adjustment upon translation
Responsive postural adjustment upon translation will be assessed through Motor Control Test and Adaptation Test on a computerized dynamic posturography (Bertec® Balance Advantage® Dynamic system, Bertec® Corporation, Columbus, USA). During the Motor Control Test, participants will be requested to maintain their standing balance in response to 12 translations of the standing platform in either forward or backward direction with medium and large amplitudes. Weight symmetry, latency of reaction and amplitude of sway will be recorded. Full-body safety harness will be worn throughout the tests to protect the participants from any potential loss of balance.
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Time frame: Pre-intervention, 1 week after intervention and 4 months after intervention.
Responsive postural adjustment upon tilting
Responsive postural adjustment upon tilting will be assessed through Adaptation Test on a computerized dynamic posturography (Bertec® Balance Advantage® Dynamic system, Bertec® Corporation, Columbus, USA). During the Adaptation Test, the force platform will either tilt up or down for a total of 10 repetitions. Sway energy will be recorded. Full-body safety harness will be worn throughout the tests to protect the participants from any potential loss of balance.
Time frame: Pre-intervention, 1 week after intervention and 4 months after intervention.
Dynamic balance
Dynamic balance will be assessed by Alternative Step Test (in the unit of seconds).
Time frame: Pre-intervention, 1 week after intervention and 4 months after intervention.
Balance confidence
Balance confidence will be measured with the Chinese version of the shortened version of Activities-specific Balance Confidence Scale (ABC-6). The scale value is from 0 to 100, with higher values representing higher balance confidence.
Time frame: Pre-intervention, 1 week after intervention and 4 months after intervention.
Functional lower body strength
Functional lower body strength will be assessed by Five-time Sit to Stand Test (in the unit of seconds).
Time frame: Pre-intervention, 1 week after intervention and 4 months after intervention.
Cognitive flexibility and executive function
Cognitive flexibility and executive function will be assessed by Trial Making Tests A and B (in the unit of seconds).
Time frame: Pre-intervention, 1 week after intervention and 4 months after intervention.
Number of laboratory falls
Participants will be exposed to one trip-like perturbation and slip-like perturbation on each foot at an unexpected time. The number of falls upon perturbations will be recorded.
Time frame: Pre-intervention, 1 week after intervention and 4 months after intervention.
Cognitive impairment
Cognitive impairment will be assessed by Abbreviated Mental Test (AMT). AMT is a 10-item test, with a 10-point scale. A score less than 6 suggests a significant cognitive deficit.
Time frame: Pre-intervention.
Depressive symptoms
Depressive symptoms will be assessed by Five-Item Geriatric Depression Scale. Participants will be asked to answer 5 questions as yes or no. The answer "no" for the first question and "yes" for the other four questions will be evaluated for depression.
Time frame: Pre-intervention.
Personality traits
Personality traits assessed by Ten-Item Personality Inventory. It has 10 items, each item adopts a 5-level score of 1 (Disagree strongly) to 5 (Agree strongly), and a higher dimension score indicates a stronger individual's personality proneness.
Time frame: Pre-intervention.
Generic preference-based quality-of-life
Generic preference-based quality-of-life will be assessed by five-level EuroQol five-dimensional questionnaire (EQ-5D-5L). The EQ-5D-5L essentially consists of 2 parts: the EQ-5D descriptive system and the EQ visual analogue scale (EQ VAS). In the EQ-5D descriptive system, each dimension has 5 levels: no problems, slight problems, moderate problems, severe problems and extreme problems. Each health state is identified by a five-digit code, with 11111 representing the best and 55555 the worst possible health state. In the EQ CAS, the scale value is from 0 to 100, with higher values representing higher balance confidence.
Time frame: Pre-intervention, 1 week after intervention and 4 months after intervention.
Muscle activations
Muscle activations will be assessed by surface electromyography using an electromyography system (Trigno IM, Delsys Inc., Natick, MA, USA). Fourteen electrodes are placed bilaterally over erector spinae, rectus abdominis, gastrocnemius medialis, biceps femoris, rectus femoris, tibialis anterior, and gluteus medius according to the SENIAM guidelines (www.seniam.org) by the physical therapist.
Time frame: Pre-intervention, 1 week after intervention and 4 months after intervention.
Physical activity
Physical activity will be assessed by the Physical Activity Scale for the Elderly. This questionnaire will ask participants to recall their activity over the last 7-days. Activity types include sitting, walking, sport/recreation, exercise, occupational and household. A total score for physical activity can be calculated using these answers and the predetermined weights associated with each activity.
Time frame: Pre-intervention, and 4 months after intervention