The "Strategies for Defibrillation during Out-of-Hospital Cardiac Arrest" (STRAT-DEFI) trial is an investigator-initiated, individually randomized, 3-group clinical trial comparing standard anterior-lateral pad positioning with anterior-posterior positioning and double sequential defibrillation during adult out-of-hospital cardiac arrest.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
909
Defibrillation pads positioned anterior-lateral
Defibrillation pads positioned anterior-posterior
Combination of anterior-lateral and anterior-posterior pad positioning for a total of 4 pads and 2 shocks.
Emergency Medical Services, the North Denmark Region
Aalborg, Denmark
RECRUITINGDanish Air Ambulance, Danish Regions
Aarhus N, Denmark
NOT_YET_RECRUITINGPrehospital Emergency Medical Services, Central Denmark Region
Aarhus N, Denmark
Survival at 30 days
Time frame: 30 days after the cardiac arrest
Survival at 90 days
Time frame: 90 days after the cardiac arrest
Favorable neurological outcome at 30 days
Neurological outcome will be assessed with the modified Rankin Scale (mRS) which is a scale from 0 to 6 assessing neurological/functional outcomes after brain damage with higher scores indicating worse neurological/functional outcomes. The scale will will be dichotomized as favorable (mRS 0-3) vs. unfavorable (mRS 4-6).
Time frame: 30 days after the cardiac arrest
Favorable neurological outcome at 90 days
Neurological outcome will be assessed with the modified Rankin Scale (mRS) which is a scale from 0 to 6 assessing neurological/functional outcomes after brain damage with higher scores indicating worse neurological/functional outcomes. The scale will will be dichotomized as favorable (mRS 0-3) vs. unfavorable (mRS 4-6).
Time frame: 90 days after the cardiac arrest
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Copenhagen Emergency Medical Services, the Capital Region of Denmark
Ballerup Municipality, Denmark
NOT_YET_RECRUITINGThe Prehospital Center, Region Zealand
Næstved, Denmark
NOT_YET_RECRUITINGEmergency Medical Services, the Region of Southern Denmark
Vejle, Denmark
NOT_YET_RECRUITING