Randomized contralateral eye study to evaluate the effect of one-time dosing of NV701 versus commercially available 1.25% pilocarpine solution on pupil size.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
DOUBLE
Enrollment
55
eye drop
eye drop
Arizona Eye Center
Chandler, Arizona, United States
Global Research Management, Inc
Glendale, California, United States
Change in pupil size over 8 hours
Area under the curve (AUC) of the change in mesopic pupil diameter over 8 hours after eye drop dosing
Time frame: 8 hours
Mesopic pupil diameter difference
Absolute difference in mesopic pupil diameter at 1, 2, 3, 4, 5, 6, 7, and 8 hours after administration
Time frame: 8 hours
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