OSAS is a disease characterized by repeated interruptions and restarts of breathing during sleep. Respiratory muscle sarcopenia is a condition in which the muscle strength of the diaphragm and other respiratory auxiliary muscles decreases, resulting in a decrease in breathing effort. Decreased respiratory effort is an important indicator of OSAS. Age, presence of chronic disease, and obesity increase the presence and severity of respiratory sarcopenia. If OSAS is left untreated, it leads to cardiovascular diseases, dementia, Alzheimer's and even death in early adulthood. In recent years, studies have shown that continuous positive airway pressure (CPAP), as well as healthy behavior development, preventive health and exercise measures, are important in the management of these diseases. There is no research in the literature on the evaluation of respiratory muscle sarcopenia in OSAS patients. This study aims to evaluate respiratory muscle sarcopenia in OSAS based on a concrete value reflecting respiratory muscle strength and/or volume.
In the study, respiratory muscle sarcopenia will be evaluated in OSAS patients. It will be evaluated whether the expiratory pressure value, peek flow meter value and 6-minute walking distance are predictors of respiratory sarcopenia for OSAS.
Study Type
OBSERVATIONAL
Enrollment
150
Tarsus University
Mersin, Mersin, Turkey (Türkiye)
Anthropometric measurement
Waist circumference, hip circumference will be measured, waist-hip ratio will be calculated.
Time frame: 1 year
BOdy mass measurement
Body weight,fat-free mass (FFM) and appendicular skeletal muscle mass (ASMM) and skeletal muscle mass expressed in kilograms will be measured by bioelectrical impedance.
Time frame: 1 year
Hand Grip strength
Jamar hand dynamometer, which is recommended by the American Association of Hand Therapists (AETD) and has been found to have high validity and reliability in many studies and is therefore considered the gold standard, will be used to measure hand grip strength.
Time frame: 1 year
Walking speed
Walking speed will be measured with the 4 Meter Walking Speed Test (4MYHT).
Time frame: 1 year
Respiratory muscle strength:
Respiratory muscle strength will be evaluated with a portable, electronic mouth pressure measurement device.
Time frame: 1 year
Expiratory flow rate
Peak expiratory flow (PEF), also called peak expiratory flow rate (PEFR) and peak flow measurement, will be measured with a PEFmeter (MSA 100 PEFmeter), a small, hand-held device used to monitor a person's ability to breathe air.
Time frame: 1 year
Respiratory function test
To evaluate pulmonary functions(FEV1/FVC ve FEV1 ), it will be measured in a sitting position with a Spirolab III brand spirometer according to ATS/European Respiratory Society (ERS) criteria.
Time frame: 1 year
Functional capacity
Functional exercise capacity will be evaluated with the 6-minute walk test (6MWT)
Time frame: 1 year
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