Evaluation of Efficacy and Safety Parameters of Different Antibiotics Regimens for Management of Empyema

Fayoum University90 enrolled

Overview

To evaluate the impact of using different antibiotic regimens including single and combined agents as the empirical therapy and evaluate the clinical outcomes regarding safety, efficacy, and pharmacodynamics parameters.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Empyema, Pleural

Interventions

Levofloxacin + clindamycinDRUG

Group 1

Levofloxacin + cefipimeDRUG

Group 2

Moxifloxacin + meronamDRUG

Group 3

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: Confirmed Diagnosis of Empyema: Patients with a clinical and radiological diagnosis of Exclusion Criteria: 1 - Hypersensitivity or Allergy to the selected antibiotic: Patients with a known history of hypersensitivity or allergic reactions to used antibiotics. 2- Pregnancy and Lactation

Locations (1)

Fayoum University hospital

Al Fayyum, Faiyum Governorate, Egypt

RECRUITING

Outcomes

Primary Outcomes

Evalutate different antibiotics

To evaluate the impact of using different antibiotic regimens including single and combined agents as the empirical therapy .

Time frame: 2 weeks

Central Contacts

Abdelrahman Ahmed Mohamed, Teaching Assistant

CONTACT

+0201145154500 aa4496@fayoum.edu.eg

Marwa Kamal Tolba, Assistant professor

CONTACT

+201067789982 mka05@fayoum.edu.eg

Data from ClinicalTrials.gov

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