Evaluating Ultrasound-Guided Needle Knife for Dupuytren's Contracture

Mohamed Maher Ismail Ahmed Elashmawy30 enrolled

Overview

This study aims to evaluate the efficacy and safety of ultrasound-guided needle knife dissection in treating Dupuytren's contracture. The procedure is designed to improve hund function and minimize complications associated with the conventional surgical methods.

Dupuytren's contracture is a disease mainly characterized by the progressive fibrosis of the palmar fascia with subsequent hand deformity and dysfunction. The current study seeks to explore, through this minimally invasive technique, ultrasound-guided needle knife dissection regarding ROM and patient satisfaction. The procedure will be carried out under ultrasound guidance to ensure safety and completeness with the accuracy of precise dissection. Primary outcome measures will concern hand mobility, and secondary measures will evaluate patient self-reported satisfaction and any complications for the 6-month follow-up period.

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Dupuytren Contracture

Interventions

Ultrasound guided needle knife dissectionPROCEDURE

This procedure involves a minimally invasive dissection of the fibrous cords in Dupuytren's Contracture using a needle knife guided by ultrasound imaging. Local anesthesia using 3-5 ml of 1% Lidocaine and 0.25% bupivacaine is administered for patient comfort. The technique aims to improve precision, minimize complications and reduce recurrence. Device: Sonosite M-Turbo Ultrasound Machine with Linear Probe HFL38x (6-13 MHz) is used for real-time imaging during the procedure.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Participants diagnosed with Dupuytren's Contracture. * Willing to undergo ultrasound-guided needle knife dissection Exclusion Criteria: * Patients who have undergone previous surgery or needle apponeurotomy for Dupuytren's Contracture on the same hand. * Active hand infections, open wounds, or dermatological conditions in the treatment area. * Coagulopathy or use of anticoagulant that cannot be safely paused * Neuromuscular disorders affecting hand function * Pregnancy or breastfeeding * Uncontrolled systemic illnesses, such as poorly managed diabetes or cardiovascular disease. * Known hypersensitivity to local anesthetics.

Locations (1)

Mansoura University Hospital

Al Mansurah, Dakahlia Governorate, Egypt

RECRUITING

Outcomes

Primary Outcomes

Improvement in hand Function

Functional Improvement: \- Evaluated using the QuickDASH score (0-100 scale).

Time frame: 6 months

Improvement in hand mobility

Range of Motion (ROM): \- Measurment of joint mobility in degrees at MCP and PIP joints by goniometer.

Time frame: 6 months

Secondary Outcomes

Patient Satisfaction

Evaluation of patient-reported satisfaction using a standardized questionnaire.

Time frame: 6 months

Rate of procedure-related complications

Monitoring and documentation of procedure-related complications, including infection, nerve injury, and other adverse events.

Time frame: 6 months

Central Contacts

Mohamed Maher Elashmawy, MD, PHD.

CONTACT

+201004303100 mohamedmaherismail@mans.edu.eg

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.