Comparison of the Postoperative Analgesic Effects of SPSIPB and TPB in Mastectomy Operations

Ankara Etlik City Hospital60 enrolled

Overview

Breast cancer is the most common malignancy in women, and surgery is one of the cornerstone treatments for breast cancer. Postoperative pain can significantly reduce patients' quality of life and acute pain may even trigger chronic pain syndrome. Nerve blocks reduces opioid consumption in the postoperative period by providing better pain control and therefore has advantages such as fewer side effects and less risk of pulmonary and cardiac complications. In this study; it was aimed to compare the analgesic effectiveness of serratus posterior superior intercostal plane block and thoracic paravertebral block in the postoperative period in patients who underwent mastectomy.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Enrollment

Conditions

Mastectomy Peripheral Nerve Block Pain Management

Interventions

Serratus posterior superior intercostal plane block will be performed on the patients using 30 ml of 0.25% bupivacaine under ultrasound guidance. Additionally, in the postoperative period a paracetamol dose of 1 g every 8 hours and a dexketoprofen dose of 50 mg twice daily were administered iv for multimodal analgesia.

Thoracic Paravertebral BlockPROCEDURE

Thoracic paravertebral block will be performed on the patients using 30 ml of 0.25% bupivacaine under ultrasound guidance. Additionally, in the postoperative period a paracetamol dose of 1 g every 8 hours and a dexketoprofen dose of 50 mg twice daily were administered iv for multimodal analgesia.

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients aged 18-80 years * American Society of Anesthesiologists (ASA) score I-II-III * Body Mass Index (BMI) between 18-30 kg/m2 Exclusion Criteria: * Patients under 18 and over 80 years of age * ASA score IV and above * Patients with a history of bleeding diathesis * BMI below 18 or above 30 kg/m2

Outcomes

Primary Outcomes

Pain Scores

Pain will be assessed at rest and while coughing using the visual analog scale on a scale from 0 (no pain) to 10 (worst pain). Pain assessment will be done at 0st, 1st, 2nd,4th, 12th, and 24th hours after surgery.

Time frame: On the operation day

Secondary Outcomes

Intraoperative opioid consumption

Remifentanil consumption for intraoperative period will be recorded

Time frame: Intraoperative period

Postoperative Tramadol Consumption

Tramadol consumption for 24 hours will be recorded

Time frame: On the operation day

Central Contacts

Atakan Sezgi, MD

CONTACT

00905323327000 kansezgi@gmail.com

Mustafa Sırrı Kotanoğlu, Associate Professor