To evaluate the efficacy and safety of different adjuvant treatment options after surgery for early high-risk breast cancer with BRCA1/2 mutation HR+/HER2
Study Type
OBSERVATIONAL
Enrollment
300
BRCA1/2 mutated hormone receptor-positive HER2-negative early high-risk breast cancer is treated with 3 3 treatment options after surgery:Endocrine drug +CDK4/6 inhibitor or PRAP inhibitor or Endocrine drug +CDK4/6 inhibitor+PARP inhibitor
Cancer Hospital, Chinese Academy of Medical Sciences
Beijing, Beijing Municipality, China
Invasive Disease-Free Survival rate
Time frame: 3 years
Distant relapse-free survival rate
Time frame: 3 years
Overall survival rate
Time frame: 3 years
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