Objective: To assess the burden and the transmission dynamics of Mycoplasma genitalium (MG) infection in men who have sex with men in Hong Kong. Design and setting: involving a) a cross-sectional study (completion of an online self-administered survey, followed by self-sampling for testing in the laboratory, and performance of HIV self-test); b) a mathematical modelling study to simulate the transmission dynamics of MG infection and resistant MG infection and compare the impacts of test-and-treat strategies. Participants: Around 920 men who have sex with men would be recruited
Cross-sectional study: A total of 920 men who have sex with men aged 18 or above and normally living in Hong Kong would be recruited. Eligible participants would be asked to complete a self-administered online survey, submit self-collected urine specimen and rectal swabs for Chlamydia trachomatis, Neisseria gonorrhoeae, and Mycoplasma genitalium testing in the laboratory, and submit HIV self-test results. Mathematical modelling study: A compartmental model would be constructed to simulate the transmission dynamics of MG infection and resistant MG infection, and analyse the impact of different test-and-treat strategies.
Study Type
OBSERVATIONAL
Enrollment
920
The Chinese University of Hong Kong
Hong Kong, Hong Kong
RECRUITINGprevalence of MG infection
detection of MG infections in self-collected samples divided by the total number of samples collected
Time frame: 1 year
prevalence of MG resistance mutations
detection of MG resistance mutations macrolide/fluoroquinolone in MG positive samples divided by the total number of MG positive samples
Time frame: 1 year
prevalence of CT infection
detection of CT infections in self-collected samples divided by the total number of samples collected
Time frame: 1 year
prevalence of NG infection
detection of NG infections in self-collected samples divided by the total number of samples collected
Time frame: 1 year
co-infection of STIs
number of co-infection of HIV, CT, NG, and/or MG
Time frame: 1 year
history of STI and HIV testing
number of self-reported history of STI and/or HIV testing at survey
Time frame: ever
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