Urethral PeRfusion Index-Guided Hemodynamic ManagemenT in Patients Having Major Abdominal Surgery: the UPRIGHT Randomized Feasibility Trial

Universitätsklinikum Hamburg-Eppendorf116 enrolled

Overview

We will perform this single-center pilot trial to determine if the intraoperative urethral perfusion index is higher in patients assigned to maintaining postinduction baseline urethral perfusion index than in patients assigned to routine care (with blinded urethral perfusion index monitoring). As pre-planned substudies, we will also assess the agreement between a) urethral perfusion index-derived pulse rate and heart rate measured with an electrocardiogram and b) between the urethral perfusion index and the peripheral perfusion index.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

116

Conditions

Urethral Perfusion Index Tissue Perfusion Microcirculation

Interventions

Eligibility

Sex: ALLMin age: 45 Years

Medical Language ↔ Plain English

Inclusion Criteria: * at least 45 years old * scheduled for elective major abdominal surgery (involving visceral organs with an expected duration of at least 120 minutes) * indication for an arterial catheter * indication for an urinary catheter Exclusion Criteria: * Pregnancy * Planned surgery: nephrectomy, liver or kidney transplantation surgery * Patients who previously had surgery on the urethra or bladder * Patients without clinical indication for continuous blood pressure monitoring with an intraarterial catheter

Locations (2)

University Medical Center Hamburg-Eppendorf

Hamburg, Germany

NOT_YET_RECRUITING

University Medical Center Hamburg-Eppendorf

Hamburg, Germany

RECRUITING