Ultrasound Assessment of Gastric Volume in High-Risk Pregnant Women At Term

N/ANot Yet RecruitingNCT06803225

The Chaim Sheba Medical Center500 enrolled

Overview

The risk of pulmonary aspiration of gastric contents remains a significant risk during anesthesia, especially in pregnant women, as they may often require surgery without having observed appropriate fasting. A bedside ultrasound assessment of the status of the gastric content would be of great value for the clinician. This prospective observational study aimed to (1) qualitatively and quantitatively describe the sonographic appearance of the gastric antrum in fasted high-risk pregnant women during the third trimester and (2) evaluate the relationship between demographic and clinical variables and the gastric antral cross-sectional area (CSA).

The aim of this prospective study is to provide a qualitative and quantitative description of the sonographic appearance of the gastric antrum in fasted high-risk pregnant women in the 3rd trimester. The investigators expect that the information obtained from the systematic ultrasonographic qualitative/quantitative assessment of the gastric content may help anesthesiologist to better assess aspiration risk and guide anesthetic and airway management, particularly in pregnant women scheduled for elective Cesarean delivery after standard preoperative fasting guidelines.

Study Type

OBSERVATIONAL

Enrollment

500

Conditions

Pregnancy Respiratory Aspiration of Gastric Content

Interventions

Eligibility

Sex: FEMALEMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Non-labouring pregnant women at 3rd trimester (≥ 28 weeks) 2. 18 years or older. 3. ASA physical status I-III 4. Hospitilized in High Risk Pregnancy Department 5. Ability to understand the rationale of the study assessments and provide signed informed consent. 6. Written informed consent Exclusion Criteria: 1. Patients with American Society of Anesthesiology (ASA) physical status class IV. 2. Patient age \< 18 years 3. Pregnant patients with upper gastrointestinal (GI) disease and pathology. 4. History of upper GI tract surgical procedures. 5. History of medications that affect gastrointestinal motility. 6. Inability to understand the rationale of the study assessments and provide signed informed consent.

Outcomes

Primary Outcomes

Qualitative assessment of the antrum of the stomach

Patients will be classified as follows; Grade 0: the antrum appears empty on both supine and right lateral decubitus positions; grade 1: gastric fluid is visible on the right lateral decubitus position only, suggesting a small fluid volume; and grade 2: gastric fluid is observed in the antrum in both supine and right lateral decubitus, suggesting a larger fluid volume.

Time frame: 10 min

Secondary Outcomes

Quantitative assessment of the antrum of the stomach

Three consecutive measures of the CSA (cross sectional area) of the antrum will be calculated via the ultrasound machine (free tracing method).