Comparison of Endometrial Protein Profile in Spontaneous Versus Stimulated Menstrual Cycles in Poor Responders

N/ACompletedNCT06804174

University Medical Centre Ljubljana15 enrolled

Overview

Evaluation of endometrial protein profile in spontaneous and stimulated menstrual cycles

Study Type

INTERVENTIONAL

Allocation

Purpose

BASIC_SCIENCE

Masking

NONE

Enrollment

Conditions

Proteome

Interventions

use of gonadotropinsOTHER

Comparison of endometrial proteome during the window of implantation between stimulated and spontaneous cycles.

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 43 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Primary infertility 2. Poor ovarian response Exclusion Criteria: 1. Normal or high ovarian response to gonadotropin stimulation 2. Menstrual cycle disorders 3. Severe male cause of infertility 4. Preimplantation genetic testing 5. Pathological findings of the uterus (fibroids, endometrial polyps, adenomyosis) and fallopian tubes (distal occlusion of one or both fallopian tubes with hydrosalpinx).

Locations (1)

Division of Obstetrics and Gynecology, university Medical Centre Ljubljana

Ljubljana, Slovenia

Outcomes

Primary Outcomes

Analysis of endometrial proteome after the use of gonadotropins

Comparison of endometrial proteome during the window of implantation between spontaneous and stimulated cycles.

Time frame: From enrollment to the end of treatment (approximately 2 months).

Data from ClinicalTrials.gov

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