Investigators assume that surgical correction approach to functional mitral regurgitation during intervention for chronic aortic regurgitation in patients with severe enlargement of the left heart chambers influences reverse remodeling of the left ventricle (LV) in the postoperative period. It is suggested that functional mitral regurgitation (MR) provides supra-physiological left ventricle volume overload and this fact plays positive role in early-stage post-operative left ventricle volume and function recovery. LV volume, systolic and diastolic function will be monitored with echocardiography (EchoCG) along with life quality in patients with different grades of functional mitral regurgitation secondary to severe chronic aortic insufficiency after surgical treatment of aortic regurgitation.
Study Type
OBSERVATIONAL
Enrollment
120
observation only
Petrovsky National Research Center of Surgery
Moscow, Russia
RECRUITINGVoronezh Regional Clinical Hospital No. 1
Voronezh, Russia
RECRUITINGLV end-diastolic volume (EDV) decrease
Change in end-diastolic volume of the left ventricle, assessed with EchoCG after surgical correction of aortic insufficiency
Time frame: 3 and 12 months after surgery
Freedom from readmission
Freedom from readmission due to valvular problem or heart failure-related reason
Time frame: 12 months after surgery
Life quality
The patient's life quality according to the results of the EuroQol-5D-5L (EQ-5D-5L) questionnaire (0-100 points, the higher - the better).
Time frame: Upon inclusion, 10 days post-surgery, 3 month and 12 month post-surgery
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