Clinical and Radiographic Outcome of Regeneration in Immature Permanent Human Teeth Using a New Scaffold

Ain Shams University22 enrolled

Overview

This study aimed to evaluate clinical and radiographic outcome of regeneration in immature permanent human teeth using two different types of scaffolds: 1. Collagen-hydroxyapatite scaffold (Osteon III collagen) after blood clot. 2. Conventional blood clot scaffold.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Randomized Clinical Trial

Interventions

Osteon III collagenDRUG

Hydroxyapatite and tricalcium phosphate particles embeded in bovine collagen

Blood clotBIOLOGICAL

Induction of bleeding from apical papilla

Eligibility

Sex: ALLMin age: 6 YearsMax age: 15 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: 1. Single rooted immature permanent teeth. 2. Symptoms: 1. Pulp necrosis either due to infection or trauma. 2. Periapical condition; tooth should have periapical radiolucency. 3. Tooth should be restorable without the need for further post placement. 4. Age: from 6-15 years. 5. Sex: males or females. 6. Preoperative Cone beam Computed tomography is a must. Exclusion Criteria: * Teeth with complete root formation. 2. Teeth that are badly broken down with difficult isolation. 3. Medically compromised patients. 4. Periodontally affected teeth.

Locations (1)

AinShams university

Cairo, Egypt

Outcomes

Primary Outcomes

Root completion of immature teeth

Root completion of immature teeth will be measured in terms of increase in root length, dentin thickness and apical foramen closure

Time frame: 1 year follow up

Secondary Outcomes

positive sensibility test

Time frame: 1 year follow up

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.