Transcriptomic Analysis and Optical Coherence Tomography Combined for Patients With Basal Cell Carcinoma

Bispebjerg Hospital50 enrolled

Overview

The goal of this observational study is to learn if tape strip for transcriptomic (RNA) analysis and optical coherence tomography (OCT) combined can optimize noninvasive management of basal cell carcinoma (BCC) patients. The main question of the study is to examine if the combination of these two techniques, transcriptomic and OCT, can improve noninvasive detection of human BCCs. All included patients will undergo 1) an OCT scan and 2) a tape strip collection for transcriptomic analysis from the same BCC.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Basal Cell Carcinomas

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients \> 18 years with clinical suspicious BCC for inclusion in the study and BCC histopathology diagnosis for inclusion in our analysis. Exclusion Criteria: * Patients with a BCC in areas not amenable to OCT (e.g., around the eye).

Locations (1)

Department of Dermatology, Bispebjerg Hospital

Copenhagen, Denmark

Outcomes

Primary Outcomes

Association between tape strip and OCT

The association between BCC-specific image marker profiles from OCT and BCC-specific transcriptomic profiles from tape strips, in histopathologically confirmed BCC patients.

Time frame: Single time point at baseline examination

Data from ClinicalTrials.gov

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