This study mainly evaluated the safety and tolerability of HRS-1893 in subjects with non-obstructive hypertrophic cardiomyopathy, and the efficacy and plasma concentrations of different dosing regimens in subjects with non-obstructive hypertrophic cardiomyopathy.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
84
HRS-1893 tablet.
HRS-1893 tablet placebo.
Fuwai Hospital
Beijing, Beijing Municipality, China
RECRUITINGAdverse events (AEs)
Time frame: Up to 14 weeks.
The incidence of left ventricular ejection fraction (LVEF) < 50%
Time frame: Up to 14 weeks.
Peak oxygen uptake (pVO2) value
Time frame: About 12 weeks.
The cardiac troponin value
Time frame: About 12 weeks.
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