A Clinical Study of SHR-2004 Injection in Preventing Venous Thromboembolism in Patients Undergoing Total Knee Arthroplasty

Inclusion Criteria: 1. Understand the research procedures and methods, volunteer to participate in this trial, and sign the informed consent form in writing; 2. Planned elective schedule total knee arthroplasty (TKA) patients; 3. Men or women who are ≥ 18 years old and \< 80 years old on the day of signing the informed consent form. Exclusion Criteria: 1. Unable to receive CT angiography of both lower limbs; 2. Malignant tumor within one year of the screening; 3. Myocardial infarction, transient ischemic attack or ischemic stroke occurred within 6 months of the screening; 4. Any medical history that may increase the risk of bleeding or any conditions that the investigator considers to increase the risk of bleeding; 5. History of drug abuse; 6. Pregnant or lactating women.