Thiol Disulfide Balance and Oxidative Stress Change in Endometrial Polyp Patients

N/ACompletedNCT06826495

Mardin Artuklu University54 enrolled

Overview

Changes in Thiol Disulfide Balance and Oxidative Stress Mechanisms in Patients with Endometrial Polyps

Study Type

OBSERVATIONAL

Enrollment

54

Conditions

Endometrial Polyp Oxidative Stress

Eligibility

Sex: FEMALEMin age: 20 YearsMax age: 48 Years

Medical Language ↔ Plain English

Inclusion Criteria: For participants in the control group: • To be without endometrial polyp For the polyp group, they were as follows: * Individuals experiencing menometrorrhagia * A body mass index (BMI) of 25 or more * Hypertension * Endometrial polyps detected via saline infusion ultrasonography Exclusion Criteria: * Pregnancy * Diabetes mellitus * Pelvic mass * Malignancy * The use of Tamoxifen, hormonal contraceptives, or hormone replacement therapy.

Locations (1)

Alanya Training and Research Hospital Gynecology and Obstetrics Department

Antalya, Turkey (Türkiye)

Outcomes

Primary Outcomes

Oxidative stress markers

Total antioxidant status (μmol Trolox equivalent/ L)

Time frame: From January 2021 to January 2022

Oxidative stress markers

Total oxidant status (μmol H2O2 equivalent/L)

Time frame: From January 2021 to January 2022

Oxidative stress markers

Oxidative stress index (arbitrary unit)

Time frame: From January 2021 to January 2022

Oxidative stress markers

Paraoxonase (U/L)

Time frame: From January 2021 to January 2022

Oxidative stress markers

Arylesterase (Ku/l)

Time frame: From January 2021 to January 2022

Oxidative stress markers

Total thiol (µmol / L)

Time frame: From January 2021 to January 2022

Oxidative stress markers

Native thiol (µmol / L) / alb (g / l)

Time frame: From January 2021 to January 2022

Oxidative stress markers

Disulfide (-S-S-) (µmol / L) / alb (g/l)

Time frame: From January 2021 to January 2022

Oxidative stress markers

Ischemia-modified albumin (u/L)

Time frame: From January 2021 to January 2022

Data from ClinicalTrials.gov

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NCT06826495 - Thiol Disulfide Balance and Oxidative Stress Change in Endometrial Polyp Patients | Crick | Crick