161Tb-NYM032 is a radiopharmaceutical labeled with a PSMA ligand, used for the treatment of metastatic castration-resistant prostate cancer, which is needed for clinical trial to be conducted.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
15
The initial dose is set at 30 mCi.
The dose will be escalated to 50 mCi.
The dose will be escalated to 80 mCi.
PSA
PSA levels can be used to monitor the treatment efficacy, disease progression, or recurrence of prostate cancer. A decrease in PSA levels after treatment usually indicates effective therapy, while an increase in PSA levels may suggest disease recurrence or progression.
Time frame: 5-6 weeks after each administration.
68Ga-NYM032 PET/CT
\*\*Reflect the PSMA expression level in the patient's lesions.\*\*
Time frame: **5-6 weeks after the second and fourth administrations in the same dose-escalation cohort.**
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
The dose will be escalated to 130 mCi.
The maximum dose is set at 200 mCi.