Establish the First International Database on Semi-quantitative Values Obtained in Scintigraphy With Datscan® in Cadmium-Zinc-Telluride Camera

N/ANot Yet RecruitingNCT06828705

Central Hospital, Nancy, France300 enrolled

Overview

Datscan scintigraphy is a nuclear medicine examination allowing the diagnosis of neurodegenerative pathologies linked to damage to dopaminergic pathways, such as Parkinson's disease (essential for the differential diagnosis of essential tremor). There are several types of cameras allowing its performance: * Conventional Anger cameras and, * CZT (Cadmium-Zinc-Telluride) semiconductor cameras. At the Nancy University Hospital, the nuclear medicine department has a wide-field Cadmium-Zinc-Telluride camera: VERITON-CT (Spectrum Dynamics). The interpretation of this examination is purely visual. The objectives are therefore to: * Create the first international database of semi-quantitative values in 3D scintigraphy with Datscan performed with a VERITON-CT camera. * Compare this database with another database from a conventional Anger camera (Lyon Nuclear Medicine Department) to show its superiority.

Study Type

OBSERVATIONAL

Enrollment

300

Conditions

Neurodegenerative Diseases

Interventions

datscan scintigraphyOTHER

Semi-quantitative analysis on Datscan imaging scintigraphy

Eligibility

Sex: ALLMin age: 18 YearsMax age: 99 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Adult patients who have undergone a Datscan scintigraphy on the VERITON camera in the nuclear medicine department of the Nancy University Hospital and who have an established clinical diagnosis, -Absence of neurodegenerative pathology or Parkinson's disease or Lewy body disease. * The clinical diagnosis can only be established after two years of clinical follow-up. Exclusion Criteria: * Excluded from this research will be the patients opposed to the use of their data, minors, atypical Parkinsonian syndromes, * patients who died before two years of clinical follow-up, * patients who had their Datscan examination carried out on a camera other than the VERITON and - patients lost to follow-up.

Outcomes

Primary Outcomes

To create the first international database of Datscan by camera VERITON-CT.

Fixation ratio of central gray nuclei of the brain namely, the global striatum, caudate nuclei, putamens

Time frame: One day

Secondary Outcomes

Compare this database with another database from another type of camera (Lyon nuclear medicine team) to show its superiority.

Identical to the primary evaluation criterion compared to those of the Lyon database.

Time frame: One day

Central Contacts

Antoine VERGER, MD,PhD

CONTACT

0383153911 a.verger@chru-nancy.fr

Veronique ROCH, MsC

CONTACT

0383154276 v.roch@chru-nancy.fr

Data from ClinicalTrials.gov

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