KTRSensor Scotland Study: An Observational Study Into Predictors and Diagnosis of Kidney Transplant Rejection

University of Edinburgh200 enrolled

Overview

An observational study capturing real world transplant patients in the post-operative setting aiming to further determine the utility of biomarkers to improve outcomes.

A prospective longitudinal observational study capturing patients receiving kidney transplants in Scotland. The primary objective is to assess whether there are clinical biomarkers present in the urine that determine the outcome of kidney transplants and predict early graft rejection.

Study Type

OBSERVATIONAL

Enrollment

200

Conditions

Kidney Transplant Kidney Disease, Chronic

Eligibility

Sex: ALLMin age: 18 YearsMax age: 99 Years

Medical Language ↔ Plain English

Any patient within a Scottish Transplant centre who has undergone renal transplant (+/- pancreas/islet) and is due to attend routine follow-up appointments at the index centre. Exclusion criteria: * no previous kidney transplant * patient attending follow-up at a peripheral site * unable to provide urine samples across the study duration

Locations (2)

Royal Infirmary of Edinburgh

Edinburgh, United Kingdom

RECRUITING

Queen Elizabeth University Hospital

Glasgow, United Kingdom

RECRUITING

Outcomes

Primary Outcomes

Number of participants that experience acute transplant rejection

Defined by gold standard core biopsy, reported using the Banff histology grading.

Time frame: 12 months

Central Contacts

Alexander J Le Saint-Grant, MBChB

CONTACT

+44 131 651 8100 Lex.LeSaint-Grant@ed.ac.uk

Data from ClinicalTrials.gov

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