The aim of this study is to learn more about how physical activity and cardiorespiratory fitness are related to diabetes risk among breast cancer patients prescribed an endocrine therapy.
80 women between the ages of 18-80 years will be recruited for this study. The study design consists of two separate in-person visits to University of Colorado Anschutz Medical Campus or Colorado State University. The study consists of glucose testing, a body composition scan, exercise testing, and a two-week period of free living activity monitoring.
Study Type
OBSERVATIONAL
Enrollment
40
No intervention is performed. Participants who have been treated with either a SERM or aromatase inhibitor are recruited and analyzed in separate groups, but the study design for all participants is identical.
University Of Colorado Anschutz Medical Campus
Aurora, Colorado, United States
Insulin Resistance
Insulin resistance will be measured through oral glucose tolerance testing
Time frame: Immediately after the consent form is signed
Body Composition
Body composition will be measured through DEXA scan
Time frame: Immediately after the insulin resistance measurement
Maximal Exercise Capacity
Maximal exercise capacity measured through graded exercise test on stationary bicycle
Time frame: Within 2-60 days of insulin resistance measurement
Daily Activity
Daily activity measured using activity monitor
Time frame: 2-60 days following insulin resistance measurement
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