Study of the Oral Treatment MTR-601 in Cervical Dystonia

Participants who meet ALL the following inclusion criteria will be eligible to participate in the study: 1. Willing to adhere to study procedures and provide written informed consent prior to the start of any study procedures. 2. Confirmed clinical diagnosis of cervical dystonia with the following: * Treatment with botulinum toxin injections (any type) on a stable dosing regimen for ≥ 2 consecutive doses at V2 or a history of botulinum toxin injections within the last 5 years which were discontinued for reasons other than lack of efficacy. * 3 months (90 days) since botulinum toxin injection (≥6 months (180 days) for daxibotulinum toxinA) at V3 * TWSTRS total score ≥ 20 with the following sub scores at V2: * Severity ≥ 15 * Disability ≥ 3 * Pain score ≥ 1) * Willingness to not use botulinum toxin for duration of their study participation 3. Adults 18-80 years of age at the time of consent. 4. Weight ≥40 kg and body mass index (BMI) ≤35 kg/m2. 5. Agree to practice highly effective birth control starting at screening and continuing for 30 days (females) or 90 days (males) after study treatment ends. * For females any of the following (no donation of eggs/ova is allowed): * Abstinence from heterosexual intercourse. * Postmenopausal: absence of menses ≥ 12 months (without an alternative medical condition) and FSH ≥ 40 mIU/mL at screening. * Surgically sterile: bilateral oophorectomy, salpingectomy, tubal ligation, or hysterectomy ≥180 days prior to screening. * Contraceptive implant or intrauterine device. * For males any of the following: * Abstinence from heterosexual intercourse. * Male condom with spermicide or male condom with vaginal spermicide (gel, foam, or suppository). * Surgically sterile: post vasectomy or bilateral orchiectomy ≥180 days prior to screening. * No donation of sperm is allowed Participants who meet ANY of the following criteria will be excluded from participation in the study: 1. History of, or physical examination findings indicating, clinically significant endocrine, neurological, gastrointestinal, cardiovascular, hematological, hepatic, immunological, renal, respiratory, genitourinary, or muscle abnormalities or diseases that, in the opinion of the Investigator, renders the participant unsuitable for the study. 2. History of any of the following: * Cervical dystonia due to trauma * Chronic contractures in the head and neck musculature * Generalized dystonia of any type * Myasthenia gravis (MG) or amyotrophic lateral sclerosis (ALS) 3. Use of the following treatment for cervical dystonia: * Botulinum toxin (of any type) within 3 months (90 days) (6 months (180 days) for daxibotulinum toxinA) at Baseline (V3) * Baclofen by intrathecal pump within 6 months (180 days) months at Baseline (V3) * Any previous history of deep brain stimulation or surgery intended to treat or correct cervical dystonia (e.g. myectomy) * Other treatments for cervical dystonia (anti-cholinergic, muscle relaxants such as flexeril or oral baclofen, or benzodiazepines) are allowed if the dose has been stable for ≥3 months (90 days). 4. Use of the following medications within 2 weeks prior to V3: * CYP3A inhibitors, inducers and substrates. * BCRP substrates: rosuvastatin, sulfasalazine 5. Use of the following food or beverages which might interact with MTR-601 within the last week prior to V3: \- Grapefruit juice or food products containing Seville orange extract (e.g. British orange marmalade, bitter orange liqueurs) 6. History of significant hypersensitivity, intolerance, or allergy to any drug compound, food, or other substance, that, in the opinion of the Investigator, renders the participant unsuitable for the study. 7. Active neoplastic disease or history of any neoplastic disease within 5 years of screening (except for basal or squamous cell carcinoma of the skin or carcinoma in situ that has been definitively treated with standard of care). 8. Active infection (e.g., sepsis, pneumonia, abscess) or a serious infection (e.g., resulting in hospitalization or requiring parenteral antibiotic treatment) within 6 weeks prior to dosing. 9. History of stomach or intestinal surgery or resection that would potentially alter absorption and/or excretion of orally administered drugs (uncomplicated appendectomy and hernia repair are allowed). 10. Any of the following at screening (V2) (if any of these conditions are found on initial ECG, a repeat ECG is allowed in consultation with the medical monitor): * QT interval corrected for heart rate using Fridericia's formula (QTcF), QRS duration, PR interval outside of normal limits confirmed by repeat measurement, unless deemed non-clinically significant by PI and agreed by Medical Monitor * Findings which would make QTc measurements difficult or QTc data uninterpretable * History of additional risk factors for Torsades de Pointes (e.g., heart failure, hypokalemia, family history of long QT syndrome) 11. Positive urine alcohol screen or positive urine drug screen (including amphetamines, cocaine, opiates, or barbiturates), at screening (V2). * Benzodiazepines will be allowed if prescribed for cervical dystonia, and on a stable dose for ≥3 months (90 days) at screening (V2). * Cannabis use and cannabinoid positive drug screen is allowed. * Smoking and cotinine positive screen is allowed. 12. Positive hepatitis panel and/or positive human immunodeficiency virus test at screening (V2). 13. Any of the following laboratory values at screening or on Day -1, as confirmed by 1 repeat if necessary: * Hemoglobin \<11 g/dL for females, and \<12 g/dL for males * Absolute neutrophil count (ANC) \<1.5 × 109 /L (\<1500/μL). * Aspartate aminotransferase (AST), alanine aminotransferase (ALT), gammaglutamyl transferase (GGT), alkaline phosphatase (ALP), or total bilirubin \>1.5 × upper limit of normal (ULN) at screening or on Day -1, confirmed by 1 repeat if necessary. 14. Participation in a clinical study involving administration of an investigational drug (new chemical entity) or medical device within the last 90 days or 5 half-lives of the investigational medication, whichever is longer, prior to dosing. 15. Receipt of blood products within 2 months prior to Day -1. 16. Donation of blood (\>400 mL) or comparable blood loss (\>350 mL) from 3 months prior to screening, plasma donation from 2 weeks prior to screening, or platelets donation from 6 weeks prior to screening. 17. Participants who, in the opinion of the Investigator (or designee; including input from participants' general practitioner, as applicable), should not participate in this study. 18. Participants who are investigational site staff members or directly involved in the conduct of the study and their family members or participants who are employed by the Sponsor. 19. Pregnant or nursing (lactating) females