Efficacy of Platelet-Rich Plasma Injection in Dry Eye Syndrome

Centre Hospitalier Universitaire de Nice20 enrolled

Overview

The investigatror wants to show the efficacy of Platelet-Rich Plasma injection in lacrimal gland to restore the lacrimal secretion in patients presenting aqueous deficiency reponsible for severe dry eye syndrome.

injections in lacrimal gland four times during the study for each patient

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Severe Dry Eye Syndromes Dry Eye Syndromes

Interventions

injections of Platelet-Rich Plasma in lacrimal glandOTHER

injections of Platelet-Rich Plasma in lacrimal gland

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Platelet counts, and clotting factors in the standarts * Presenting with severe dry keratoconjunctivitis diagnosed by an ophthalmologist Exclusion Criteria: * Patients with significant fibrosis of the conjunctival portion of the lacrimal gland * Patients with complete stenosis of both lacrimal meatus in the treated eye

Locations (1)

CHU de Nice

Nice, Site Principal Investigator, France

RECRUITING

Outcomes

Primary Outcomes

To compare the lacrimal secretion after 4 monthly injections of PRP into the lacrimal gland

Schirmer I test score between 0mm and more 20mm

Time frame: week 16

Secondary Outcomes

To compare the different clinical follow-up parameters of qualitative dry ocular syndrome and quantitative after 4 monthly injections of PRP into the lacrimal gland

Ocular Surface Diseases Index (OSDI) a scale of 0 to 100

Time frame: week 16

Central Contacts

Doctor Jean Philippe GROSSE, Dr

CONTACT

04.92.03.47.02 causeret.m@chu-nice.fr

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.