The aim of this study was to determine the effects of two different exercise protocols on body composition, aerobic capacity, blood lipid profile, some biomarkers, quality of life and exercise beliefs in participants at risk of diabetes.
After being informed about the study and possible risks, all participants who gave written informed consent and met the eligibility requirements will be randomly assigned to 2 separate groups.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
24
1 minute interval, 1 minute active recovery 5 minutes warm-up - 3 minutes cool-down will be done at 60% of peak heart rate. Weeks 1-2: Loading at an intensity of 85% of peak heart rate, active recovery at an intensity of 60% of peak heart rate 4x1 Weeks 2-7: Loading at an intensity of 90% of peak heart rate, active recovery at an intensity of 60% of peak heart rate 6x1 Weeks 8-12: Loading at an intensity of 90% of peak heart rate, active recovery at an intensity of 60% of peak heart rate 8x1
5 minutes warm-up - 3 minutes cool-down will be done at 60% of peak heart rate. Weeks 1-2: Loading at 65% of peak heart rate intensity (22 minute) Weeks 2-7: Loading at 75% of peak heart rate intensity (30 minute) Weeks 8-12: Loading at 75% of peak heart rate intensity (38 minute)
University of Kyrenia Hospital
Mersin, Kyrenia, Turkey (Türkiye)
RECRUITINGEastern Mediterranean University
Mersin, Turkey (Türkiye)
RECRUITINGHbAc
It is the amount of glycosylated hemoglobin in the blood.
Time frame: 12 weeks
HDL
It is the amount of high-density lipoprotein in the blood.
Time frame: 12 weeks
LDL level LDL
It is the amount of low-density lipoprotein in the blood.
Time frame: 12 weeks
CRP
C-reactive protein is a protein produced in the liver.
Time frame: 12 weeks
Total cholesterol
Cholesterol is a lipid that is necessary for the construction of cell membranes in the body and the production of some hormones and vitamin D.
Time frame: 12 weeks
Triglyceride
It is a type of fat molecule found in the bloodstream and is used as the body's energy source.
Time frame: 12 weeks
Irisin
Irisin, defined as a myokine, is the proteolytic product of fibronectin type III domain 5 protein.
Time frame: 12 weeks
Adiponectin
Adiponectin is a protein hormone and adipokine, which is involved in regulating glucose levels and fatty acid breakdown.
Time frame: 12 weeks
IL-6
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Interleukin-6 is an endogenous chemical involved in inflammation and B cell maturation.
Time frame: 12 weeks
Resistin
Resistin is a hormone secreted from fat cells.
Time frame: 12 weeks
Kemerin
It is a protein that is involved in many metabolic events such as adipogenesis, angiogenesis and glucose homeostasis, including the chemoattractant function of the belt.
Time frame: 12 weeks
Osteocalcin
Osteocalcin is a bone-specific protein found in osteoblasts.
Time frame: 12 weeks
Leptin
Leptin is a hormone that acts on the hypothalamus through negative feedback secreted from fat cells, suppressing food intake and increasing energy expenditure.
Time frame: 12 weeks
TNF-alpha
Tumor necrosis factor alpha is a chemical messenger produced by the immune system that initiates inflammation.
Time frame: 12 weeks
Cardiometabolic risk level
Cardiometabolic risk has been defined as a cluster of metabolic and cardiovascular abnormalities, including abdominal obesity, insulin resistance, hypertension, dyslipidemia, and atherosclerosis, that predispose individuals to cardiovascular disease and type 2 diabetes.
Time frame: 12 weeks
Body composition
Body composition describes the amount of fat, bone, water and muscle in the body.
Time frame: 12 weeks
Aerobic capacity
Aerobic capacity is the capacity of large striated muscle groups to adapt to work using energy obtained from aerobic metabolism.
Time frame: 12 weeks
Exercise Health Belief Model Scale
Exercise Health Belief Model Scale is a 5-point Likert-type scale consists of 32 items.The scale consists of 5 factors and there is no reverse item. The highest and lowest score on the scale is 160 and 32, respectively. Higher scores indicate higher level of exercise health belief.
Time frame: 12 weeks
Short Form-36 Questionnaire
The Short Form (36) Health Survey is a 36-item, patient-reported survey of patient health. SF-36 measures eight scales: physical functioning, role physical, bodily pain, general health, vitality, social functioning, role emotional, and mental health.Each scale is directly transformed into a 0-100 scale on the assumption that each question carries equal weight. High scores indicate good health status.
Time frame: 12 weeks