The Prophylactic Effect of Garlic Tablets to Prevent Nosocomial Infections in Intensive Care Unit Patients.

Phase 3Enrolling By InvitationNCT06833125

Alexandria University62 enrolled

Overview

The goal of this clinical trial is to learn if garlic tablets works to prevent nosocomial infections in hospitalized patients in ICU. The main questions it aims to answer are: Does garlic tablets administration lower the occurence of nosocomial infections in hospitalized patients in ICU?

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Enrollment

Conditions

Nosocomial Infection

Interventions

Garlic powder standardized to allicinDRUG

The intervention is the administration of garlic tablets (Tomex plus 300 mg) two tablets twice daily (which contains 5.4 mg allicin the active ingredient with anibacterial effect) for 6 days just after ICU admission

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * All patients aged from 18 to 65 years old admitted to intensive care units without any type of infection. Exclusion Criteria: 1. Patients with signs /symptoms of infection. 2. Patients with human immunodeficiency virus, malignancy and patients with a history of recent immunosuppressants or corticosteroids administration. 3. Patients with bleeding disorders or abnormal coagulation profile 4. Patients who will planned for surgery within 2 weeks.

Locations (1)

Alexandria Main University Hospital

Alexandria, Alexandria Governorate, Egypt

Outcomes

Primary Outcomes

Occurrence of central line-associated bloodstream infections, catheter- associated urinary tract infections, surgical site infections and ventilator- associated pneumonia in the two groups (by cultures results).

Time frame: one year

Secondary Outcomes

Values of Blood white cell count, body temperature and C-reactive protein of the patient in the two groups .

The Mean of Blood white cell count (number per micro liter) , body temperature ( by the degree Celsius) and C-reactive protein (milligrams per liter ) of the patients in the two groups will be calculated.

Time frame: one year

Values of Blood white cell count, body temperature and C-reactive protein of the patient in the two groups .

The Mean of Blood white cell count, body temperature and C-reactive protein of the patient in the two groups will be calculated.

Time frame: one year

Data from ClinicalTrials.gov

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