This work evaluated the systemic effect of different preoperative carbohydrate (CHO) loads in pediatrics undergoing elective surgery.
Children undergoing surgery experience stress due to disruptions in their daily routine and exposure to various perioperative circumstances that induce anxiety and pain. The management of perioperative nutrition in pediatric patients is a crucial aspect of patient care. The concept of preoperative carbohydrate (CHO) loading has gained attention as a potential strategy to mitigate these drawbacks. The administration of a CHO-rich drink two hours preoperative has been proposed to maintain euglycemia, decline IR, and enhance postoperative recovery
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
90
A preoperative carbohydrate load was done two hours before the operation using a10 ml/kg, with a maximal volume of 250 ml of commercial brand of apple juice (glucose 28 g in 250 ml).
A preoperative carbohydrate load was done using 1.75mg/kg/dose of anhydrous glucose (Alpha Chmika).
Patients received water.
Tanta University
Tanta, El-Gharbia, Egypt
C-reactive protein (CRP) level
C-reactive protein (CRP) level was assessed two h before surgery as baseline, at induction of anesthesia, and 4 hours after the operation.
Time frame: 4 hours postoperatively
Neutrophil/ lymphocyte ratio
Neutrophil/ lymphocyte ratio (NLR) was assessed 2 h before surgery as baseline, at induction of anesthesia, and 4 hours after the operation.
Time frame: 4 hours postoperatively
Level of procalcitonin
Level of procalcitonin was assessed two h before surgery as baseline, at induction of anesthesia, and 4 hours after the operation.
Time frame: 4 hours postoperatively
Homeostatic model assessment for insulin resistance
Homeostatic model assessment for insulin resistance(HOMA.IR) was assessed two h before surgery as baseline, at induction of anesthesia, and 4 hours after the operation.
Time frame: 4 hours postoperatively
Level of C-peptide
Level of C-peptide was assessed two h before surgery as baseline, at induction of anesthesia, and 4 hours after the operation.
Time frame: 4 hours postoperatively
Level of random blood glucose
Level of random blood glucose (RBG) was measured at two hours before the surgery.
Time frame: Two hours before the surgery
Patient's parent's satisfaction
Parent satisfaction level was evaluated by 3-point Likert scale (1, unsatisfied; 2, neutral; 3, satisfied).
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Time frame: 4 hours postoperatively
Incidence of complications
Incidence of complications such as perioperative nausea, vomiting, and aspiration were documented.
Time frame: 4 hours postoperatively