Evaluation of Neuromuscular Blockade Responses in Statin-Using and Non-Using Patients

Inclusion Criteria: * Age 18-75 years * ASA classification I, II, III * BMI 18-30 * Statin use for at least 3 months or no prior statin use * Elective surgery requiring general anesthesia with endotracheal intubation * Signed informed consent for participation in the study Exclusion Criteria: * ASA classification IV or higher * BMI \<18 or \>30 * History of liver or renal insufficiency (creatinine \>1.6, liver function tests \>2x normal) * Neuromuscular, psychiatric, or neurological disorders * Pregnancy * Use of drugs affecting neuromuscular function (e.g., anticonvulsants, aminoglycosides) * History of malignant hyperthermia * Respiratory disorders, including sleep apnea * Allergy to anesthetic drugs used in the study