The objective of this Phase 1 study is to assess the safety and efficacy of single treatment of AGN-151586 and of OnabotulinumtoxinA in the glabellar complex of participants with moderate to severe glabellar lines (GL).
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
132
Investigate MD /ID# 270771
Scottsdale, Arizona, United States
Eye Research Foundation /ID# 270827
Newport Beach, California, United States
Marcus Facial Plastic Surgery /ID# 270770
Redondo Beach, California, United States
Number of Participants with Adverse Events (AEs)
An AE is defined as any untoward medical occurrence in a patient or clinical investigation in which a participant is administered a pharmaceutical product which does not necessarily have a causal relationship with this treatment.
Time frame: Up to approximately 10.4 months
Number of Participants with the Presence of Binding and Neutralizing Antidrug Antibodies to AGN-151586 and/or OnabotulinumtoxinA
Samples collected from participants treated with AGN-151586 and OnabotulinumtoxinA will be analyzed for antibodies against both AGN-151586 and OnabotulinumtoxinA.
Time frame: Up to approximately 10.4 months
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Skin Research Institute LLC /ID# 270831
Coral Gables, Florida, United States
Skincare Physicians /ID# 271018
Chestnut Hill, Massachusetts, United States
Wilmington Dermatology Center /ID# 270828
Wilmington, North Carolina, United States
Austin Institute for Clinical Research - Pflugerville /ID# 270834
Pflugerville, Texas, United States
SkinDC /ID# 270932
Arlington, Virginia, United States