Clinical Diagnosis of Acute Appendicitis with Normal WBCS Count with Role of Inflammatory Markers and Radiology

N/AActive Not RecruitingNCT06834958

Assiut University50 enrolled

Overview

The aim of this study is to describe the proportion of pa-tients with normal preoperative inflammatorymarkers among patients with histopathologically proven acute appendicitis

2.4.1- Type of the study: prospective clinical trial study 2.4. 2- Study Setting: Assuit university hospital 2.4. 3- Study subjects: 1. Inclusion criteria: patients complain of Rt iliac pain with Us positive for acute appendicitis with WBCS normal . 2. Exclusion criteria: malignant mass cancer appendix mesenteric adentis cecal diverticulum salpingitis c. Sample Size Calculation: 50 cases 2.4.4 -Study tools (in detail, e.g., lab methods, instruments, steps, chemicals, …): Lab WBCS count CRP level Neutrophil differential count Clinical correlation US findings and MSCT if needed

Study Type

OBSERVATIONAL

Enrollment

Conditions

Acute Appendicitis

Interventions

AppendectomyPROCEDURE

Open surgery for appendix which is inflamed

Eligibility

Sex: ALLMin age: 14 DaysMax age: 60 DaysHealthy volunteers:

Medical Language ↔ Plain English

Inclusion * Male or female patients é clinically diagnosed acute appendicitis with normal WBCS Exclusion Criteria: * complicated AA (perforation, peri appendicular abscess or suspicion of a tumor. 2\_inflammatory bowel diseases 3\_inability to co-operate and give informed consent 4\_diffuse peritonitis 5\_Patients with serious comorbid conditions DM \& renal insufficiency, serum creatinine \> 150 μmol/l 6\_Pregnant \& lactating patient 7\_Patients with advanced malignancies \& pt on immunosuppressive drugs

Locations (1)

Assuit university

Asyut, Egypt

Outcomes

Primary Outcomes

Surgery done if needed

Patient with acute appendicitis and normal WBCS count will be under observation for while but people with evidence on imaging and high inflammatory markers will go under surgery

Time frame: Days of hospital reservation

Data from ClinicalTrials.gov

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