We study efficacy of iv nalbuphine in prevention of intrathecal morphine-induced nausea and vomiting in patients undergoing cesarean section.
IV nalbuphine has been proved to help prevent intrathecal morphine-induced pruritus in some studies but results in nausea vomiting prevention have not been well studied. In Thailand, most caesarean section is done under spinal anesthesia with intrathecal morphine, proving that iv nalbuphine is effective would be beneficial for our population. This study aims to see whether 4 mg of nalbuphine is effective in reducing incidence of intrathecal morphine-related nausea vomiting in parturient who underwent C-section under spinal anesthesia with 0.2 mg of intrathecal morphine.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Enrollment
180
prevention of nausea vomiting
Department of Anesthesiology, Faculty of Medicine, Thammasat University
Pathum Thani, Changwat Pathum Thani, Thailand
Faculty of Medicine Thammasat University
Pathum Thani, Changwat Pathum Thani, Thailand
Incidence of postoperative nausea vomiting in 24 hours
Time frame: 24 hours
Severity of nausea vomiting
Time frame: 24 hours
Postoperative pain score
Time frame: 24 hours
Incidence of pruritus
Time frame: 24 hours
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