The goal of this clinical trial is to learn if transjugular intrahepatic portosystemic shunt (TIPS)-guided AI model can guide TIPS procedure in adults better than conventional TIPS procedure (artificially blinded TIPS). TIPS surgical outcomes and intraoperative and postoperative complications will also be observed. The main questions it aims to answer are: * Does the AI model lower the number of punctures, radiation dose, and complications of participants undergo TIPS? * Does the AI model improve the efficacy of TIPS for participants? Participants will: * Take the TIPS by the guidance of the AI model or conventional manually blinded penetration (placebo) * The number of punctures, the success rate of the procedure, the radiation dose, intraoperative complications and postoperative complications within 3 months will be recorded * Intraoperative portal pressure gradient drop values, symptoms of ascites and rebleeding within 3 months after TIPS will be reported
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
180
The TIPS procedure will be conducted under the guidance of AI model which was constructed based on the pre-operation enhanced CT images and intra-operation DSA images.
The TIPS procedure will be conducted based on the experience of operators.
Wuhan Union Hospital
Wuhan, Hubei, China
Wuhan Union Jinyinhu Hospital
Wuhan, Hubei, China
Wuhan Union West Hospital
Wuhan, Hubei, China
Number of punctures
The number of punctures is defined as the number of punctures to the liver during the establishment of the puncture channel during the TIPS procedure.
Time frame: From the beginning to the end of the TIPS procedure.
Radiation dose
Radiation dose from the TIPS procedure.
Time frame: From the beginning to the end of the TIPS procedure.
Surgical success rate
Procedural success was defined as the success of placing a stent and reducing the portal pressure gradient during the TIPS procedure
Time frame: From the beginning to the end of the TIPS procedure.
Complications
Complications are defined as bleeding, infection, and other complications due to puncture.
Time frame: From enrollment to the end of the TIPS procedure at 3 months.
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