This is a pilot open study to test the hypothesis that home-based transcranial static magnetic field stimulation (tSMS) of the supplementary motor area is safe and feasible to modulate corticostriatal activity in patients with Parkinson's disease.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
20
Transcranial static magnetic field stimulation (tSMS) is a non-invasive brain stimulation (NIBS) technique that decreases cortical excitability. Static magnetic fields suitable for tSMS are obtained with commercially available neodymium magnets. The investigators will use a cylindrical neodymium magnet of 60 mm diameter and 30 mm of thickness (MAG60r; Neurek SL, Toledo, Spain), which will be applied with south polarity to the supplementary motor area (SMA) using an ergonomic helmet (MAGsv1.1, Neurek SL, Toledo, Spain).
HM CINAC, Hospital Universitario HM Puerta del Sur, HM Hospitales
Móstoles, Madrid, Spain
RECRUITINGAdverse events (safety)
Number of device-related AE
Time frame: From the start to 3 months after the end of treatment (5 months)
Feasibility of home-based tSMS
Number of home-based tSMS sessions completed, according to patient's diaries
Time frame: From the start to the end of treatment (8 weeks)
Subjective improvement
Patient global impression of change (PGIC)
Time frame: Within one week after the end of treatment compared to baseline
Motor improvement
MDS-UDPRS III scale
Time frame: Within one week after the end of treatment compared to baseline
Sleep improvement
SCOPA-sleep scale
Time frame: Within one week after the end of treatment compared to baseline
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.