Evaluation of Effectiveness and Safety of Stabilized Injectable Hyaluronic Acid (Perleux Body, Produced by Espad Pharmed Company) in the Neck Area

Inclusion Criteria: * Age between 35 and 60 years (inclusive) * The presence of visible signs of skin aging, mainly dry neck skin, rough neck skin, loss of elasticity and clear lines and wrinkles (grades 2, 3, and 4 based on the IBSA Neck Laxity Scale) * Able to follow study instructions and likely to complete all required visits * Signing the informed consent form and agreeing to the 6-month follow-up Exclusion Criteria: * Previous treatment with fillers containing hyaluronic acid in the neck area during the last year * History of using RF, rejuvenating lasers or intense pulsed light in the last 6 months * Having systemic diseases that affect skin health, such as vascular collagen diseases, diabetes, hypothyroidism, liver and kidney failure. * History of systemic use of drugs affecting the skin such as glucocorticoids, isotretinoin, immunomodulators and hormonal drugs in the last 3 months * History of taking supplements containing collagen, hyaluronic acid and vitamin C in the last 3 months * History of using topical corticosteroids and retinoids in the last 4 weeks * Using topical cosmetic products containing anti-aging ingredients in the last 2 weeks * Pregnant and lactating women * History of active smoking during the last 2 years * Major change in lifestyle including diet and physical activities and sun exposure during the study * History of previous allergy to hyaluronic acid or lidocaine * Any inflammation, active infection, unhealed old wound, and skin lesions in the injection area * Using any anticoagulant product, NSAID, or any other drug that increases the risk of coagulation disorders, in the last 7 days * History of anaphylactic shock * Being prone to hypertrophic scar formation * History of autoimmune disease or immune deficiency or using immunosuppressant drugs