Anastomotic leakage (AL) is a serious complication after surgery for colon cancer, leading to a significant increase in mortality.Intraoperative fluorescence imaging using indocyanine green has proven to be a feasible and reproducible technique for real-time perfusion assessment. An increasing number of studies are being published on the use of indocyanine green (ICG) fluorescence imaging in colorectal cancer surgery, showing promising results. Therefore, we propose conducting a multicenter, randomized controlled trial to investigate the potential use of quantitative assessment of near-infrared fluorescence imaging with indocyanine green (ICG) to prevent anastomotic leaks during colorectal surgery.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
1,268
ICG will be injected before anastomosis is created, to quantitatively assess the perfusion status of the bowel.
conventional perfusion assessment
BELOOSTROV Clinic of High Technologies
Vsevolozhsk District, Leningradskaya Oblast', Russia
30-days Anastomotic Leakage (AL) rate
Anastomotic leakage rate
Time frame: 30-days
complication rate
Time frame: 30-days
mortality
Time frame: 30-days
days in hospital stay
Time frame: 90-days
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