Infusion of beta-hydroxybutyrate can suppress endogenous glucose production, which may result in increased net liver glycogen storage. If ketone esters exert similar effects, then the increase in liver glycogen storage may have implication for recovery from exercise and subsequent exercise performance. The aim of this study is to assess the effects of ketone esters ingested during recovery from exercise, on metabolism and subsequent exercise capacity.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Enrollment
18
0.29 g per kilogram body mass per hour of ketone monoester (R)-3-hydroxybutyrate (R)-3-hydroxybutyl
Medium chain triglycerides and bitter tastant (Bitrex)
University of Bath
Bath, Bath, United Kingdom
Glucose concentrations
Blood glucose concentrations during the recovery period (240 minutes)
Time frame: 240 minutes
Non-oxidative fate of ingested sucrose
Non-oxidative fate of ingested glucose measured by appearance of 13C on breath CO2 from high 13C sucrose ingested during recovery
Time frame: 240 minutes
Exercise capacity
Time to exhaustion running at 70% of maximal aerobic capacity after the recovery period
Time frame: 240 minutes
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