In this study, 300 patients aged ≥18 years old with traumatic brain injury (case group) and hospitalized patients without central nervous system disease or their family members and accompanying staff (control group) were selected as the study objects. At baseline, participants completed the Mini-mental State Examination (MMSE), the Loewenston Occupational Therapy Cognitive Assessment (LOTCA) battery, the Glasgow Coma Scale (GCS), and the Alzheimer's Disease Rating Scale Cognitive Subscale (ADAS-Cog11). The evaluation process of the first LOTCA test was videotaped by a person. 2 weeks after the evaluation, the same two scale raters watched the video and rated it independently again. After 3 months, the subjects completed MMSE, LOTCA battery, GCS, ADAS-Cog11 assessment again.
Study Type
OBSERVATIONAL
Enrollment
300
The study was observational and did not involve any intervention.
The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University
Huaian, Jiangsu, China
Suzhou Jiulong Hospital
Suzhou, Jiangsu, China
The Affiliated Hospital of Xuzhou Medical University
Xuzhou, Jiangsu, China
Northern Jiangsu People's Hospital
Yangzhou, Jiangsu, China
Evaluator Reliability of the Loewenston Occupational Therapy Cognitive Assessment (LOTCA) battery
Time frame: At baseline
Retest Reliability of the Loewenston Occupational Therapy Cognitive Assessment (LOTCA) battery
Time frame: 2 weeks Later
Internal Consistency Reliability of the Loewenston Occupational Therapy Cognitive Assessment (LOTCA) battery
Time frame: At baseline
Content Validity of the Loewenston Occupational Therapy Cognitive Assessment (LOTCA) battery
Time frame: At baseline
Construct Validity of the Loewenston Occupational Therapy Cognitive Assessment (LOTCA) battery
Time frame: At baseline
Discriminative Validity of the Loewenston Occupational Therapy Cognitive Assessment (LOTCA) battery
Time frame: At baseline
The change of Loewenston Occupational Therapy Cognitive Assessment (LOTCA) battery score from baseline values
Time frame: 3 months later
The change of Alzheimer's Disease Assessment Scale - Cognitive Subscale 11 score from baseline values
Time frame: 3 months later
Correlation between LOTCA score change from baseline and ADAS-Cog11 score change from baseline
Time frame: 3 months later
The area under ROC curve and the sensitivity, specificity and Jorden index under optimal threshold of LOTCA score change from baseline value
Time frame: 3 months later
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