An Exploration of the Relationship Between Serum Cytokine Levels and the Clinical Efficacy of Vedolizumab

Second Affiliated Hospital of Wenzhou Medical University105 enrolled

Overview

It is uncertain the relationship between serum cytokine levels and the clinical efficacy of vedolizumab in the treatment of ulcerative colitis. The effects of cytokines on the efficacy of vidrecizumab in Chinese UC patients were retrospectively analyzed. Methods: Patients with UC were recorded. These patients were detected the levels of cytokines.

Study Type

OBSERVATIONAL

Enrollment

105

Conditions

Ulcerative Colitis (UC)

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * UC patients Treated with Vedolizumab Exclusion Criteria: * pregnant * had cognitive/developmental disorders that affected their ability to complete the study procedures * had medical illness or therapies potentially affecting bone, nutrition or growth status

Locations (1)

The Second Affiliated Hospital of Wenzhou Medical University

Wenzhou, Zhejiang, China

Outcomes

Primary Outcomes

The partial Mayo score was applied to evaluate the clinical activity UC patients

Time frame: 16 week and 34 week

Data from ClinicalTrials.gov

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