This is a French observational, national, multicenter prospective cohort study of patients with HER2-negative eBC treated with olaparib at their physician's discretion.
The purpose to this observational study is to evaluate the rate of completion of adjuvant Olaparib treatment for HER2-negative early breast cancer patients in France.
Study Type
OBSERVATIONAL
Enrollment
126
Proportion of patients who receive Olaparib for the full treatment duration
The primary outcome is the evaluation of the proportion of patients who receive Olaparib for the full treatment duration, described as 12 months of treatment.
Time frame: 18 months after inclusion
BRCA characteristics: Mutation type
Regarding BRCA characteristics: Mutation type: Tumoral (if only tumoral testing performed), somatic, germline.
Time frame: 18 months after inclusion
Type of variants
Type of variants: BRCA1 and/or BRCA2, PALB2 mutation, presence of other HRR gene mutations, presence of other mutations
Time frame: 18 months after inclusion
Medical history
Family and personal history of cancer/type
Time frame: 18 months after inclusion
Time to Olaparib treatment discontinuation
Time to Olaparib Treatment Discontinuation (TTD) or death
Time frame: 18 months after inclusion
AstraZeneca Clinical Study Information Center
CONTACT
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Research Site
Clermont-Ferrand, Auvergne-Rh ne-Alpes, France
RECRUITINGResearch Site
Gleizé, Auvergne-Rh ne-Alpes, France
RECRUITINGResearch Site
Grenoble, Auvergne-Rh ne-Alpes, France
NOT_YET_RECRUITINGResearch Site
Lyon, Auvergne-Rh ne-Alpes, France
RECRUITINGResearch Site
Metz-Tessy, Auvergne-Rh ne-Alpes, France
RECRUITINGResearch Site
Saint-Etienne, Auvergne-Rh ne-Alpes, France
NOT_YET_RECRUITINGResearch Site
Saint-Priest-en-Jarez, Auvergne-Rh ne-Alpes, France
NOT_YET_RECRUITINGResearch Site
Thonon-les-Bains, Auvergne-Rh ne-Alpes, France
RECRUITINGResearch Site
Valence, Auvergne-Rh ne-Alpes, France
RECRUITINGResearch Site
Valence, Auvergne-Rh ne-Alpes, France
NOT_YET_RECRUITING...and 48 more locations