Does the administration of the probiotic Lactobacillus plantarum sp. have an impact on reducing leukocyte levels, segmented neutrophil counts, postoperative pain, and length of hospitalization in patients with diffuse peritonitis caused by perforated acute appendicitis who underwent laparotomy appendectomy at Dr. Hasan Sadikin Hospital?
To determine whether the administration of the probiotic Lactobacillus plantarum sp. to patients with diffuse peritonitis caused by appendiceal perforation undergoing laparotomy appendectomy at Hasan Sadikin Hospital Bandung and Siloam Karawaci Hospital has a significant effect on leukocyte levels, segmented neutrophil counts, postoperative pain levels, and length of hospitalization compared to the placebo group.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
50
Once daily consumption
Group who received a placebo intervention
Hasan Sadikin General Hospital
Bandung, West Java, Indonesia
White Blood Cells Level
A white blood count measures the number of white blood cells (WBCs) in patients' blood.
Time frame: From the day of randomization up to 5 days postoperatively
Segmented Neutrophil level
Segmented neutrophils are the most mature neutrophilic granulocytes present in circulating blood
Time frame: From the day of randomization up to 5 days postoperatively
Post operative pain level
The Visual Analogue Scale (VAS) consists of a straight line with the endpoints defining extreme limits such as 'no pain at all' and 'pain as bad as it could be'
Time frame: From the day of randomization up to 5 days postoperatively
Length of Hospital Stay
The duration of a single episode of hospitalization
Time frame: From the day of randomization up to 5 days postoperatively
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