Budesonide Nasal Irrigation Versus Fluticasone Propionate Nasal Spray in Treating Allergic Rhinitis Patients

Inclusion Criteria: * Adult age between 18 and 60 years old. * Patients with allergic rhinitis evidence by past skin prick testing. Patients were given a skin prick test with a panel of dog, cat, Dermatophagoides farinae, D pteronyssinus, Alternaria, Penicillium, Hormodendron, Aspergillus, grass pollen mix, tree pollen mix, and ragweed allergen extracts (100,000 Allergen Unit/mL). Histamine, 10 mg/mL, was used as a positive control, and the diluent was used as the negative control. A positive reaction was defined as a wheal diameter at least 3 mm greater than the diluent control and/or at least a 50-mm flare (ie, erythema measured as the sum of the greatest diameter and the perpendicular diameter through the midpoint of the greatest diameter) Exclusion Criteria: * Patients who had autoimmune diseases or any immune compromised diseases including diabetes, chemotherapy. * Patients with a history of nasal surgery. * Patients who received systemic or topical corticosteroids, herbal drugs, beta blocking agent within the previous month of enrolment. * Patients with asthma and COPD, nasal bleeding, obstructing nasal polyps, paranasal sinus.