Hyperspectral Drusen Classification

Inclusion Criteria: * To be eligible for participation, volunteers must conform to all of the following inclusion criteria: * Male and female adults aged 50 years and older (inclusive). * Dry AMD in at least one eye, with at least one type of the following retinal drusenoid deposits: reticular pseudodrusen, soft drusen, hard drusen. ○ The presence of multiple small drusen (\< 63µm) or intermediate drusen (≥63µm and ≥125µm) is sufficient to qualify for this study (Coleman, 2008). * Ability and willingness to give informed consent. Exclusion Criteria: Individuals that meet any of the following exclusionary criteria cannot be enrolled: * Any ophthalmologic condition that would prevent obtaining retinal imaging and/or could interfere with the analysis of the MHRC images and OCT images, including: * Pupil dilation contraindicated (due to a pathology or with 3 quadrants with Van Herick of 0 or 1 without iridotomy) * Inadequate pupil dilatation (\< 6mm diameter) preventing uniform illumination of the retina with the MHRC * Dry AMD presenting only with pigmentary changes or geographic atrophy (no drusenoid deposits) * Presence of geographic atrophy in a cumulative area of \>0.5 disc area * Presence of neovascular AMD, defined as the presence of at least 1 of the following 4 characteristics: serous sensory retinal detachment, RPE detachment, subretinal hemorrhage, or subretinal fibrous tissue; or history of photocoagulation for choroidal new vessels (AREDS, 2005) * Signs of vascular occlusion or retinopathy (microaneurysm, exudate, hemorrhage or edema) within a diameter of 10 mm from the mid-point between the optic nerve head and the macula (i.e. the area of interest for the MHRC imaging) * Macular dystrophy * Nuclear sclerosis \> 2 (LOCS II four-point grading system) or presence of central cortical or central posterior subcapsular cataract * Deficient visual fixation (inability to fixate for at least 2 s) * Refractive error outside the range of -15 D to +15 D * Corneal or media opacities (e.g. Weiss ring) affecting retinal imaging on a cumulative area \> 1 disc area within a diameter of 10 mm from the mid-point between the optic nerve head and the macula (i.e. the area of interest for the MHRC imaging) * Scar, atrophy, naevus, tumor, epiretinal membrane or retinal pucker with a cumulative area \> 1 disc area within a diameter of 10 mm from the mid-point between the optic nerve head and the macula (i.e. the area of interest for the MHRC imaging). * Papilledema * Inability to obtain an OCT image centered on the macular region of satisfactory quality for analysis of the drusenoid deposits (as indicated by the OCT's software quality indicator) * Inability of obtaining at least 3 images of satisfactory quality with the MHRC per the Optina Diagnostics quality index software.