The primary objective of this study is to assess the construct validity and criterion validity for associations of the VEGANScreener with nutrient intakes from reference methods and associations with biomarkers of dietary intake. The investigators hypothesize that the screener is a valid tool to assess diet quality in the vegan population. The study will assess construct validity by testing whether the measure relates as it should to other measures (e.g., age, gender, education, socioeconomic status differences). The investigators will assess concurrent and predictive validity (types of criterion validity) by evaluating associations and agreement between 'gold standards', such as diet records, biomarkers, and multi-metabolite signatures of intake. The investigators will examine associations of vegan diet quality with biomarkers of nutritional status, biomarkers of disease, and anthropometric measures and hypothesize that a higher diet quality in vegans is associated with a more favourable profile among vegans, for example, a lower blood pressure. This study is part of the European VEGANScreener Consortium.
Study Type
OBSERVATIONAL
Enrollment
200
This is an observational study
UZ Gent
Ghent, Belgium
Validity of the vegan screener
The validity will be assessed by calculating associations between the screener and reference method.
Time frame: Baseline
Dietary intake
Dietary intake will be assessed using a weighed food record
Time frame: Baseline
Food habits
Food habits will be assessed using a food frequency questionnaire
Time frame: Baseline
Vitamin D status
Vitamin D status will be measured from venous blood samples
Time frame: Baseline
Homocysteine status
Homocysteine will be measured from venous blood samples
Time frame: Baseline
holo-transcobalamin
holo-transcobalamin will be measured from venous blood samples
Time frame: Baseline
Methylmalonic acid
Methylmalonic acid will be measured from venous blood samples
Time frame: Baseline
Vitamin B2 status
Vitamin B2 will be measured from venous blood samples
Time frame: Baseline
Vitamin C status
Vitamin C will be measured from venous blood samples
Time frame: Baseline
Folic acid status
Folic acid will be measured from venous blood samples
Time frame: Baseline
Magnesium status
Magnesium status will be determined from venous blood samples
Time frame: Baseline
Zinc status
Zinc status will be determined from venous blood samples
Time frame: Baseline
Selenoprotein-P status
Selenoprotein-P status will be determined from venous blood samples
Time frame: Baseline
Ferritin concentration
Ferritin concentration will be determined from venous blood samples
Time frame: Baseline
Soluble transferrin receptor concentration
Soluble transferrin receptor will be determined from venous blood samples
Time frame: Baseline
Hemoglobin concentration
Hemoglobin will be determined from venous blood samples
Time frame: Baseline
Creatinine concentration
Creatinine will be determined from venous blood samples
Time frame: Baseline
Uric acid concentration
Uric acid will be determined from venous blood samples
Time frame: Baseline
Urea concentration
Urea will be determined from urine samples samples
Time frame: Baseline
Iodine concentration
Iodine status will be determined from urine samples
Time frame: Baseline
Potassium concentration
Potassium status will be determined from urine samples
Time frame: Baseline
Sodium concentration
Sodium status will be determined from urine samples
Time frame: Baseline
Calcium concentration
Calcium status will be determined from urine samples
Time frame: Baseline
Creatinine concentration (urine)
Creatinine will be determined from urine samples
Time frame: Baseline
C-reactive protein concentration
The inflammatory marker hsCRP will be determined from serum
Time frame: Baseline
Triglyceride concentration
Triglyceride concentration will be determine from venous blood samples
Time frame: Baseline
Free fatty acid concentration
Free fatty acid concentration will be determine from venous blood samples
Time frame: Baseline
Eicosapentanoic acid
Eicosapentanoic acid (in % of total FA) will be determine from venous blood samples
Time frame: Baseline
Docosahexanoic acid
Docosahexanoic acid (in % of total FA) will be determine from venous blood samples
Time frame: Baseline
LDL-cholesterol concentration
LDL-cholesterol concentration will be determine from venous blood samples
Time frame: Baseline
HDL-Cholesterol concentration
HDL-Cholesterol concentration will be determine from venous blood samples
Time frame: Baseline
Cholesterol concentration
Cholesterol concentration will be determine from venous blood samples
Time frame: Baseline
Glucose concentration
Glucose will be measured from venous blood samples
Time frame: Baseline
Well being
Participants well being will be assessed using a questionnaire. The scale of each question ranges from 0 to 10, 10 representing the highest well being
Time frame: Baseline
VEGANScreener
The VEGANScreener assesses diet quality using 29 questions of frequency of consumption of different foods and food groups.
Time frame: Baseline and day 2
Weight
Weight will be measured in kg
Time frame: Baseline
Height
Height will be measured in m
Time frame: Baseline
Waist circumference
Waist circumference will be measured in cm
Time frame: Baseline
Hip circumference
Hip circumference will be measured in cm
Time frame: Baseline
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