The project is a national, prospective, multicenter, observational pilot project of screening CTEPH in pacients after APE in the Czech Republic. The main goal of the project is to methodically prepare, implement and evaluate a pilot project that will verify the suitability of the proposed procedure of early detection of Chronic tromboembolic pulmonary hypertesion in such a way as to ensure the maximum positive impact on the health of the population and high cost-effectiveness of the whole process.
The project is a national, prospective, multicenter, observational pilot project of screening CTEPH in pacients after APE in the Czech Republic. The global goal of the project is to develop, test and implement a uniform procedure for early detection of patients with CTEPH and to set up a process for their rapid referral to a specialized center that treats chronic thromboembolic pulmonary hypertension. The timeliness of the treatment set up has a significant impact on patient's future quality of life and eliminates the risk of subsequent complications or death. The main objective of this activity is to validate the CTEPH screening process, which will benefit 500 patients in approximately 10 selected centres. Subsequently, patient flow from the cardiologist to a specialised pulmonary hypertension treatment centre will be ensured. The process will include a review and evaluation of the screening algorithm in patients in the pilot. The project is supported by the European Social Fund (Operational Program Employment plus) and the state budget of the Czech Republic and is registered by the Ministry of Labour and Social Affairs of the Czech Republic under ID: CZ.03.02.02/00/22\_005/0002007
Study Type
OBSERVATIONAL
Enrollment
500
Implementation of a standardized screening algorithm for early detection of CTEPH in patients after Acute Pulmonary Embolism (APE) and establishment of optimized referral of patients to specialized centers.
Brno University Hospital
Brno, Czechia
RECRUITINGHavlíčkův Brod Hospital
Havlíčkův Brod, Czechia
RECRUITINGUniversity Hospital Hradec Králové
Hradec Králové, Czechia
RECRUITINGJihlava Hospital
Jihlava, Czechia
RECRUITINGNáchod Hospital
Náchod, Czechia
RECRUITINGUniversity Hospital Olomouc
Olomouc, Czechia
RECRUITINGUniversity Hospital Ostrava
Ostrava, Czechia
RECRUITINGPardubice Hospital
Pardubice, Czechia
RECRUITINGRychnov nad Kněžnou Hospital
Rychnov nad Kněžnou, Czechia
RECRUITINGTábor Hospital
Tábor, Czechia
RECRUITINGPositive predictive value of initial examination
Examinations include echocardiography, CT scan or scintigraphy, and possibly other examinations determined by the cardiologist. Results will be collected from study enrollment to evaluation of all completed examinations by a cardiologist at the primary detection site.
Time frame: Up to six months from enrollment
CTEPH detection rates
Results will be collected from study enrollment to evaluation of all completed examinations by a cardiologist at the specialized centre.
Time frame: Up to six months from enrollment
Proportion of people with suspected CTEPH who attended a follow-up examination at a specialized pulmonary hypertension treatment centre
Examinations include echocardiography, CT scan or scintigraphy, and possibly other examinations determined by the cardiologist. Results will be collected from study enrollment to evaluation of all completed examinations by a cardiologist at the primary detection site.
Time frame: Up to six months from enrollment
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