EOIPB in Laparoscopic Cholecystectomy: Impact on Opioid Consumption Guided by ANI and Analgesia Quality

Samsun University80 enrolled

Overview

The aim of the study was to evaluate the response of regional anesthesia to remifentanyl consumption in patients undergoing laparoscopic cholecystectomy surgery.

Routine anesthesia and analgesia protocol will be applied to all participants. The study aims to evaluate the remifentanyl consumption of the participants by dividing them into two groups as those with and without block and then performing their monitoring (pulse, mean arterial pressure with noninvasive measurement, oxygen saturation, Analgesia Nociception Index, Bispectral index). Remifentanil level will be adjusted according to the ANI value. The target is to keep the ANI between 50-70.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

OTHER

Masking

DOUBLE

Enrollment

Conditions

Pain Management Laparoscopic Cholecystectomy Surgery

Interventions

Group EOİPBOTHER

Bilateral external oblique intercostal plane block under USG guidance will be applied 45 minutes before cholecystectomy surgery.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Participants who will undergo elective laparoscopic cholecystectomy surgery, * Age 18-70, * ASA I-II physical status, * Body mass index (BMI) \< 35 kg/m², * Participants who have written consent to participate in the study Exclusion Criteria: * Participants with routine analgesic consumption, * Those with coagulopathy, * Those with a history of local anesthetic allergy, * Those with cardiac arrhythmia and pacemaker, * ASA III and above, Those with dementia

Locations (1)

Samsun University, Samsun Training and Research Hospital

Samsun, İ̇lkadim, Turkey (Türkiye)

Outcomes

Primary Outcomes

Intraoperative opioid consumption

Total amount of remifentanil consumed during cholecystectomy surgery

Time frame: During surgery

Secondary Outcomes

Numeric rating scale for postoperative pain intensity

Evaluated with a Numerical rating scale (NRS) from 0 to 10. (0=no pain; 10=worst imaginable pain)

Time frame: up to 24 hours (Will be evaluated at 1, 3, 6, 9, 12, 18, 24 hours)

Quality of Recovery - 15 score

The impact of surgical and anesthetic interventions on perioperative quality of life and ability to resume routine life activities will be assessed using the Quality of Recovery (QoR) tool. Each question is scored between 0 and 10. The survey result varies between 0-150 points based on the answers given by the patients. Higher scores indicate better recovery.

Time frame: Postoperative 24th hour

Fentanyl consumption at 30 minutes after arrival in the PACU(post anesthesia care unit)

Evaluated with a NRS from 0 to 10 and fentanyl will be administered when NRS is 4 and above. Fentanyl consumed will be recorded.

Time frame: 30 minutes

Data from ClinicalTrials.gov

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