Low and Moderete Flow Anaesthesia on Haemodynamics

N/ANot Yet RecruitingNCT06871371

Umraniye Education and Research Hospital76 enrolled

Overview

The study topic investigates the potential advantages of low-flow anesthesia in terms of physiological protection and resource saving.

The study aims to compare the effects of low and normal flow sevoflurane anesthesia on the frontal QRS-T angle and cerebral oxygenation in laparoscopic cholecystectomy surgery. The primary objective was to evaluate the effects of low-flow anesthesia on hemodynamic stability and arrhythmia risk; the secondary objective was to compare the total sevoflurane consumption in both methods.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SCREENING

Masking

QUADRUPLE

Enrollment

Conditions

Hemodynamics Instability Arrhythmias Cardiac Cerebral Oxygenation

Interventions

Sevoflurane (Volatile Anesthetic)DEVICE

Both groups will be given sevoflurane and one group will be given low current anesthesia and the other group will be given medium flow anesthesia.

low- medium flow anesthetic machineDEVICE

The study aims to compare the effects of low and normal flow sevoflurane anesthesia on the frontal QRS-T angle and cerebral oxygenation in laparoscopic cholecystectomy surgery.

Eligibility

Sex: ALLMin age: 17 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria: * being ASA1-2 status * between the ages of 18-70 * who are planned for laparoscopic cholecystectomy Exclusion Criteria: * Patients who refuse to give informed consent * Pregnant and breastfeeding patients * Morbidly obese patients (Body mass index over 40) * Patients with uncontrolled diabetes mellitus, with serious cardiovascular, pulmonary, renal, hepatic disease, obstructive sleep apnea, with electrolyte imbalance- Those with a history of alcohol or drug abuse, with perioperative hemodynamic instability * Patients using drugs known to prolong myocardial repolarization * inability to increase SPO2 above 95 despite necessary intervention

Locations (1)

Umraniye Education and research hospital

Istanbul, Turkey (Türkiye)

Outcomes

Primary Outcomes

the effects of low-flow anesthesia on hemodynamic stability

The primary objective was to detect the adverse effects of low-flow anesthesia on hemodynamic stability and arrhythmia risk

Time frame: in 2 months

Secondary Outcomes

the cerebral oxygenation

The primary objective was to detect the adverse effects of low-flow anesthesia on cerebral oxygenation

Time frame: in 2 months

Central Contacts

senay goksu, specialist doctor

CONTACT

+905337144852 senaytomruk@hotmail.com

Data from ClinicalTrials.gov

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